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A Lion in the House (2006)

A Lion in the House (2006) on screen: the plot, what it portrays accurately, where drama takes over, and the real early signs and screening behind the story.

NCI source

National Cancer Institute — Cancer Information Summaries (PDQ®)

A female doctor shows a tablet to an older woman patient in a clinic room with medical charts on the wall
Clinical Care Care Scene 19

Key fact

A Lion in the House (2006) depicts childhood cancers, all treated at Cincinnati Children's Hospital: Hodgkin lymphoma (Timothy Woods), leukaemia (Alexandra.

The short answer

A Lion in the House (2006) puts cancer at the centre of its story. This page covers the plot, what the work gets right, where it takes dramatic licence, and the real medicine underneath — including early signs and whether screening exists.

  • A Lion in the House (2006) depicts childhood cancers, all treated at Cincinnati Children's Hospital: Hodgkin lymphoma (Timothy Woods), leukaemia (Alexandra.

  • Almost everything.

  • Little is dramatised; the licence lies in selection and editing.

  • A dramatised illness is not a guide to your own — but it can be a reason to ask a question you have been putting off.

About this title

Released:
2006
Format:
Documentary
Country:
United States
Director:
Steven Bognar and Julia Reichert
Cancer depicted:
Childhood cancers, all treated at Cincinnati Children's Hospital: Hodgkin lymphoma (Timothy Woods), leukaemia (Alexandra.

Search for the official trailer — we link out rather than embed a video we have not verified.

Full cast, crew and release details

This page describes a work of film or television for education. Plot details are discussed openly. Nothing here is a review of anyone’s real medical care, and a dramatised illness is not a guide to your own.

Choose how you want to understand this

The full explanation.

The story

A 225-minute documentary shot over six years at Cincinnati Children's Hospital, premiered at Sundance in 2006 and broadcast on PBS across two nights that June. It follows five children and their families. Timothy Woods, fifteen, has Hodgkin lymphoma; his cough and swollen neck were initially dismissed, he struggles with adherence and weight, responds briefly to an experimental regimen, then relapses into disease resistant to every combination tried, and dies. Alexandra Lougheed, diagnosed at five, has relapsed leukaemia, transplants and a fungal infection in her cheekbones that divides her parents over surgery; when the leukaemia returns they stop treatment and she dies at eight. Justin Ashcraft, nineteen, has endured ten years of leukaemia treatment; a stroke, paralysis and brain lesions follow a new therapy, and after a fruitless six weeks in Houston his family let him die in his sleep. Jennifer Moone finishes two years of chemotherapy and stays well, but loses IQ points and needs tutoring. Alex Fields, first misdiagnosed with asthma, completes fifteen months of chemotherapy for non-Hodgkin lymphoma and is told it will not return.

Spoilers throughout. Discussing the cancer storyline means discussing how this ends.

What it gets right

Almost everything. Because it was shot across six years rather than reconstructed, it captures what compressed drama cannot: the boredom, the repetition, the relapse that erases a year of progress, the cognitive late effects in a child who survived, the sibling who becomes clinically depressed, the mother who leaves her job and never goes back. It is unusually honest about money, following a single parent without a car and a nursing aide who cannot afford medication or unpaid leave. It shows clinicians disagreeing with each other and with parents, and it stays in the room for the moment when treatment stops being treatment and becomes something else. The children are allowed to be funny, rude, non-compliant and frightened rather than saintly.

Where the drama takes over

Little is dramatised; the licence lies in selection and editing. Six years compress into under four hours, so plateaus disappear and outcomes can look faster and more fated than they were. Three of the five children die, which is not the general picture of childhood cancer today, when most children treated for leukaemia and lymphoma survive; viewers should not read that ratio as a statistic. The protocols filmed date from the late 1990s and early 2000s and have since changed considerably, so specific drugs, doses and transplant decisions should not be taken as current practice.

The real medicine underneath

For childhood acute lymphoblastic leukaemia, NCI lists fever, easy bruising or bleeding, petechiae, weakness or fatigue, pale skin, bone or joint pain, shortness of breath, painless swollen lymph nodes in the neck, underarm, abdomen or groin, pain or fullness below the ribs, loss of appetite, weight loss, abdominal pain, and frequent or persistent infections. Hodgkin and non-Hodgkin lymphoma most often begin as painless swollen nodes, sometimes with fever, drenching night sweats, unexplained weight loss, itching, or a cough and breathlessness when nodes in the chest press on the airway, which is exactly the pattern the film shows being mistaken for asthma or a lingering cold. The single most important fact: there is no screening test for childhood cancer in children at average risk. Nothing at a routine well-child visit is designed to find it, and no blood test is recommended for symptom-free children. These cancers are found when a symptom persists and someone investigates, so the thing to act on is duration. Children with certain inherited predisposition syndromes are offered surveillance, but that is targeted, not population screening.

What to actually do with this

A film is not a diagnosis, and a dramatised illness is not a guide to your own. What a story like this is genuinely good for is lowering the barrier to a conversation you might otherwise put off.

If something in your body has changed and stayed changed for a few weeks, that is worth raising with a doctor — not because it is likely to be cancer, but because most of the time it will not be, and finding that out is the point. Where screening exists for a cancer, it is the one thing you can do before anything is wrong at all. See screening and possible warning signs.

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The bottom line

A Lion in the House is worth watching as a film. It is not a guide to the disease it portrays. The gap between the two is what this page is for — and the thing worth carrying away is that a change which persists is worth a conversation, whatever a story led you to expect.

This page describes a work of film or television for education. It is not medical advice, and nothing here is a judgement of anyone's real medical care. Spotted an error? Please email [email protected].

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A young woman lies in bed with her hand on her chest, looking concerned

Common questions

What kind of cancer is in A Lion in the House?

Childhood cancers, all treated at Cincinnati Children's Hospital: Hodgkin lymphoma (Timothy Woods), leukaemia (Alexandra Lougheed, Justin Ashcraft, Jennifer Moone) and non-Hodgkin lymphoma (Alex 'Al' Fields). This page discusses the storyline openly, including how it ends.

Is A Lion in the House medically accurate?

Little is dramatised; the licence lies in selection and editing. The full breakdown is on this page.

What are the real early signs behind this story?

For childhood acute lymphoblastic leukaemia, NCI lists fever, easy bruising or bleeding, petechiae, weakness or fatigue, pale skin, bone or joint pain, shortness of breath, painless swollen lymph nodes in the neck, underarm, abdomen or groin, pain or fullness below the ribs, loss of appetite, weight.

Should I watch this if cancer is affecting my life right now?

That is a personal decision and there is no right answer. Some people find these stories clarifying; others find them intrusive or frightening. It is entirely reasonable to skip it, or to find out how it ends before you start.

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Written by: Cancer Explained editorial teamSources last checked: 2026-07-25Last updated: 2026-07-25Next planned review: 2028-07-24

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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status — Source verified. This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

General education. Low-risk educational or organizational content. Medical facts are cited to authoritative sources.

Human medical review: not completed. Cancer Explained is not clinician-reviewed, and that is a deliberate design choice rather than a gap we are waiting to close. We restate published federal guidance and cite it; the authority belongs to the source, not to us. That is why every page names where its claims come from — so you can verify us instead of trusting us. Use it to understand your situation and to ask better questions of the people treating you.

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How this page was created

Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes. We do not employ clinicians and do not intend to — our work is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status: Source verified This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

Human medical review: not completed. Cancer Explained is not clinician-reviewed, and that is a deliberate design choice rather than a gap we are waiting to close. We restate published federal guidance and cite it; the authority belongs to the source, not to us. That is why every page names where its claims come from — so you can verify us instead of trusting us. Use it to understand your situation and to ask better questions of the people treating you.

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