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Beginner 6 min read

What to Expect When Getting a Port for Chemotherapy

A plain-language guide to getting a chemotherapy port — the minor surgery to place it, how it is used for treatment and blood draws

NCI source:NCI last reviewed 2025-05-15

Review status: AI-assisted, source checked. Not reviewed by a clinician. How we check pages

The short answer

A port is a small disc placed under your skin during minor surgery, before your chemotherapy begins. A thin tube connects it to a large vein, usually in your chest. A nurse can insert a needle through the port to give chemo or draw blood, avoiding repeated needle sticks. It stays in until treatment ends, and you should watch the area for signs of infection.

  • A port is a small, round disc placed under your skin during minor surgery, before your course of treatment begins.

  • A thin tube called a catheter connects the port to a large vein, most often in your chest.

  • A nurse inserts a needle into the port to give chemotherapy or draw blood, which avoids repeated needle sticks in your arm.

  • The needle can stay in place for treatments that last longer than one day.

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The whole article, with every detail and caution.

The short version

If your care team has recommended a port, it helps to know what it is and why it is used. A port is a small, round disc that a surgeon places under your skin during a minor surgery, before your course of chemotherapy begins. It is a common way to make repeated treatment sessions and blood draws easier on your veins.

Before the procedure

The port sits just under the skin, usually in your chest. A thin, soft tube called a catheter connects the port to a large vein, most often a vein in your chest. Your care team will talk with you about the plan and answer your questions before the day of the procedure.

During the procedure

Placing a port is minor surgery. The surgeon puts the port under your skin and threads the catheter into a large vein. Because it is a surgical procedure, your team will give you instructions to follow beforehand and afterward.

Why some people get a port

Most IV chemotherapy is given through a thin needle placed in a vein in the hand or lower arm. A port — like a catheter — is another way to receive chemotherapy that avoids repeated needle sticks in your arm. This can be especially helpful if your veins are hard to access, or if you will be getting treatment often over a long period of time.

Using your port for treatment

Once your port is in place, a nurse can insert a needle through your skin and into the port whenever you need chemotherapy or blood work. This means the nurse does not have to find a new vein each time — the needle goes into the same port. If you are having a treatment that lasts longer than one day, the needle can stay in place in the port for the full length of treatment, rather than being removed and reinserted.

Ports vs. catheters vs. pumps

It can help to know how a port compares with other devices your team might mention:

  • A port sits entirely under your skin. Nothing is outside the body, and a needle is inserted through the skin to reach it when needed.
  • A catheter is also a thin tube placed into a large vein, but the end of a catheter stays outside your body rather than being covered by skin.
  • A pump is a device that can be attached to control the flow and amount of chemotherapy you receive, sometimes used together with a port or catheter.

Your care team will recommend the option that fits your treatment plan, how long you will be receiving chemotherapy, and your veins.

Caring for your port and signs to watch for

Because a port stays under your skin for as long as your treatment continues, it is important to know the signs of infection and to tell your team right away if you notice changes around the port site. Your nurse will show you what a healthy port site looks like so you know what to watch for during your course of treatment.

After your course of treatment

The port remains in place until you finish your treatment. When your care team decides it is time, the port will be removed. Ask your team what that process involves and when you can expect it, so you know what to plan for.

Questions for your team

Every treatment plan is different, so it helps to bring your own questions to your care team. Ask why a port is being recommended for you, what the procedure involves, and how to care for the area between sessions. No question is too small about a device that will be part of your daily life during treatment.

When to get help sooner

A port sits over a large vein, so problems there are worth acting on quickly.

  • Call 911 or go to an emergency department if you get sudden chest pain or shortness of breath in the hours after the port is placed. Do not drive yourself.
  • Call your care team right away, day or night, if your temperature hits 100.4°F (38°C) or higher while you are on treatment. Call right away too for chills, a sore throat, mouth sores or burning when you urinate, even with a normal temperature. CDC says a fever during chemotherapy is a medical emergency, and that fever may be the only sign of infection. If you cannot reach the team fast, go to an emergency department and tell them you are on treatment.
  • Call your care team right away, day or night, if the skin over the port or the tunnel beneath it turns red, warm, swollen or leaks fluid. NCI says to watch for signs of infection around your port, and that infections during cancer treatment need urgent medical attention.
  • Call your care team right away if the arm, neck or face on that side starts to swell. For emergencies call 911 or go to the ER.
  • Call your care team within a day or two if the site stays sore for days after it should have settled.

Sources: National Cancer Institute — Infection and Neutropenia During Cancer Treatment; CDC — Fever During Chemotherapy.

A nurse attending to an older woman seated beside an IV pole in an infusion room

Common questions

What is a port?

A port is a small, round disc that a surgeon places under your skin during minor surgery, before your course of chemotherapy begins. A thin, soft tube called a catheter connects the port to a large vein, most often a vein in your chest.

Does getting a port require surgery?

Yes, but it is considered minor surgery. A surgeon places the port under your skin and connects it to a catheter that is threaded into a large vein before you start your course of treatment.

How is the port used during chemotherapy?

A nurse inserts a needle through your skin and into the port to give chemotherapy or draw blood. This means the nurse does not need to find a new vein in your arm or hand each time. For treatments that last longer than one day, the needle can stay in place in the port.

How long does a port stay in place?

A port is placed before you begin your course of treatment and stays in place until you finish. Ask your team what to expect when it is time for the port to come out.

What is the difference between a port and a catheter?

A port sits entirely under your skin. A catheter is also a thin tube placed into a large vein, but the end of a catheter stays outside your body rather than being covered by skin.

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Prepared by Cancer Explained's AI-assisted editorial system

Written from National Cancer Institute material and compared with the source cited below.

Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.

Last updated: 2026-09-29Next planned review: 2027-07-14

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  1. Q1.According to this article, when is a port placed?
  2. Q2.What connects the port to a large vein, according to this article?
  3. Q3.How does a port differ from a catheter, according to this article?
  4. Q4.What should you tell your care team about right away, according to this article?

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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.

Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.

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