Skip to main content
Beginner 2 min read

What Does 'Lobular Carcinoma In Situ' (LCIS) Mean?

LCIS means abnormal cells are found in the breast lobules. NCI says it raises breast cancer risk in either breast. What to ask.

NCI source:NCI Dictionary of Cancer Terms: lobular carcinoma in situ

Review status: AI-assisted, source checked. Not reviewed by a clinician. How we check pages

The short answer

Lobular carcinoma in situ, or LCIS, means abnormal cells are found in the lobules of the breast. NCI says it raises the risk of breast cancer in either breast. NCI's professional staging summary calls it a benign entity. This page explains the term and what to ask your care team.

  • NCI defines LCIS as abnormal cells found in the lobules of the breast.

  • NCI says having LCIS in one breast raises the risk of breast cancer in either breast.

  • NCI's professional summary says LCIS is a benign entity and was removed from TNM staging.

Choose how you want to read this

The whole article, with every detail and caution.

This page is for anyone whose breast biopsy report says "lobular carcinoma in situ" or "LCIS." It explains the term and what to ask your care team.

What LCIS means

NCI describes LCIS as a breast condition in which abnormal cells are found in the lobules. Lobules are the small glands that make milk.

Is it cancer?

The name includes "carcinoma," which can be alarming. NCI's breast cancer summary for health professionals says: "Lobular carcinoma in situ is a benign entity and is removed from TNM staging." Benign means not cancer.

Why it still matters

NCI says LCIS significantly raises the risk of breast cancer in either breast. That is why your care team may talk with you about follow-up and screening.

LCIS is not the same as invasive lobular carcinoma

Invasive lobular carcinoma is a breast cancer. LCIS is a different finding. Ask your care team to confirm which term is on your report.

Ask these before you leave

  • Is LCIS the only finding on my report?
  • What does it mean for my breast cancer risk?
  • What follow-up or screening do you recommend for me?

See What Does DCIS Mean?, Atypical Ductal Hyperplasia, and Invasive Lobular Carcinoma on Your Pathology Report.

Sources

A female doctor and patient look together at a tablet screen

Common questions

Is LCIS cancer?

Despite the name, NCI's professional breast summary calls LCIS a benign entity and notes it was removed from TNM staging. Ask your care team what it means for you.

Does LCIS turn into cancer?

NCI says having it raises the risk of breast cancer in either breast. Ask your care team what your follow-up should be.

How is LCIS different from DCIS?

LCIS is in the lobules, the milk-making glands. DCIS is in the lining of the ducts. Ask your care team which one your report shows.

Questions to ask your doctor

Being prepared helps you get the most out of your appointments. Save or print these questions.

Open my question list

Tap a question to save it to your list (kept on this device).

Your next step

Look up related pathology, imaging, biomarker, and treatment-response language.

Decode another report term
Talk to a person

Talk with a trained specialist or navigator

Cancer Explained provides educational guidance, but does not replace trained specialists, social workers, or your medical team.

Free & Confidential

Talk to a trained cancer information specialist

Free, confidential assistance from NCI Cancer Information Service via phone, chat, or email.

Contact your oncology team

Locate after-hours contact numbers, portal messages, or urgent triage phone lines.

Find a patient navigator

Get one-on-one help with appointments, logistics, translation, and care coordination.

Find a genetic counselor

Discuss inherited mutation risk, family history, and genetic testing options.

Find an oncology social worker

Access emotional counseling, family support groups, and mental health resources.

Find a financial navigator

Locate copay assistance foundations, grant programs, and lodging/travel support.

Find a clinical-trial specialist

Search matching studies and speak with NCI trial information specialists.

Get urgent help

Fever of 100.4°F (38°C) or higher during chemo, severe pain, or trouble breathing: call your cancer care team right away, day or night. Call 911 for an emergency.

Know someone who needs this?

Plenty of people are looking for something like this and do not know where to start. If this would help a friend or someone you love, send it on — we have written an opening line so you do not have to stare at an empty message. You can change every word of it.

Email itText itWhatsApp

Your message is written and sent in your own email or messaging app — we never see who you send it to, and nothing is added to any list.

Prepared by Cancer Explained's AI-assisted editorial system

Written from National Cancer Institute material and compared with the source cited below.

Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.

Sources last checked: 2026-10-02 what this meansLast updated: 2026-10-02Next planned review: 2027-09-27

Review details and limits

Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status — Source checked. This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.

General education — varies by person. Answers genuinely differ between people. This page explains what commonly varies and points you to your care team for your situation.

Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.

Our editorial processHow we use AIReport an error

More on this topic

Words to know

Tap any term to see what it means.

Browse the full glossary →

How this page was created

Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.

Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.

Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.

Read more about our editorial process, our use of AI, and our corrections policy.

Spotted a problem? Report an error — a factual mistake, broken or outdated source, confusing wording, or anything that seems unsafe. Please do not include names, medical record numbers, dates of birth, addresses, or other identifying medical information in your report.

After using this page, do you understand what to do next?

Anonymous — we only record the answer, never who gave it.