The short answer
During chemotherapy, some people are advised to give up pets, and MedlinePlus explains how to keep one if you decide to. The risk is infection passed from animals, and most tips point at feces, litter and tank water. Hand those chores to someone else, wash hands after contact, keep the cat's nails short and feed only commercial food. A fever of 100.4 degrees Fahrenheit or higher outranks all of it. Call your care team right away.
MedlinePlus says some people in cancer treatment may be advised to give up pets, and gives tips for keeping one safely if you decide to.
The precautions target animal waste: litter boxes, birdcages and fish tanks should be cleaned by someone else.
Neutropenia in an adult means fewer than 1,000 neutrophils per microliter; below 500 is severe neutropenia.
Cat litter should be scooped daily, with disposable pan liners, to lower toxoplasmosis risk.
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This page is for people getting chemotherapy who live with a dog, cat, bird, fish or reptile, and for the people who help care for them. It explains where the infection risk really sits and which pet chores to hand off.
Keeping a pet: what MedlinePlus advises
MedlinePlus lists cancer, including lymphoma and leukemia during treatment, among the conditions where some people are advised to give up pets. It then gives tips for people who decide to keep a pet. Ask your care team what is right for you.
The worry is zoonotic infection, meaning an infection that passes from an animal to a person.
What a low neutrophil count actually means
Neutrophils are the white blood cells that reach an infection first. Chemotherapy slows the bone marrow that makes them, so the count can fall.
MedlinePlus puts numbers on this. An adult with fewer than 1,000 neutrophils in a microliter of blood has neutropenia. Fewer than 500 is severe neutropenia. At that level, the bacteria that normally live in a person's mouth, skin and gut can cause serious infection.
MedlinePlus says to ask for your neutrophil count, not only your white cell count, when your blood is tested.
Waste is where the risk concentrates
Many of the tips in this guidance point at feces, litter and tank water.
MedlinePlus advises asking someone else to clean up after pets: no picking up pet waste, no cleaning fish tanks, no cleaning birdcages. Hand washing is listed after handling or touching a pet, after cleaning the litter box, and after disposing of pet feces. It is listed again before eating, preparing food, or taking medicines.
Cats, litter boxes, and toxoplasmosis
Toxoplasmosis is a parasitic infection that cats can pass in their feces. The guidance for a household with a litter box is unusually specific.
Keep the box away from eating areas. Use disposable pan liners, so the entire pan can be cleaned at each litter change. Have someone else change the pan where that is possible. Where it is not, rubber gloves and a disposable face mask are advised. Litter should be scooped daily, and daily scooping is named as the step that lowers toxoplasmosis risk.
Diet matters too. Cats can pick up infections such as toxoplasmosis by eating wild animals, so MedlinePlus advises feeding only commercially prepared food and treats. Raw or undercooked meat and eggs can make the animal ill.
Reptiles, birds, and fish tanks
Reptiles carry salmonella. That is stated plainly, with the advice to wear gloves when handling a reptile or its feces, because salmonella passes easily from animal to person.
Birdcages get the same treatment as litter trays, with similar precautions when they are cleaned. Fish tanks call for rubber gloves.
Ask someone else in the household to do the cleaning jobs where you can.
Scratches, bites, and which animals to avoid
Cat scratch disease is caused by a bacterium called Bartonella henselae, and cats can spread it. The advice is to keep a cat's nails short, avoid rough play, and avoid any situation likely to end in a scratch.
Age matters when adopting. MedlinePlus advises choosing an animal older than one year. Kittens and puppies scratch and bite more, and they catch infections more readily. Wild and exotic animals are advised against outright, because they bite more and can carry rare but serious diseases.
A sick pet is worth a vet visit rather than a wait. The signs listed are diarrhea, coughing and sneezing, a drop in appetite, and weight loss. Fleas and ticks spread several bacterial and viral infections, so flea collars and permethrin-treated bedding are suggested. In rare cases a dog can pass kennel cough to a person with a weakened immune system, which is a reason to avoid boarding kennels during treatment.
Fever: the number that outranks everything here
All of this becomes secondary once a fever appears. MedlinePlus lists a fever of 100.4 degrees Fahrenheit (38 degrees Celsius) or higher as a sign of infection to report right away, along with chills or sweats, redness or swelling anywhere on the body, cough and earache.
The CDC puts it more strongly: "If you get a fever during your chemotherapy treatment, it's a medical emergency." CDC says to call your doctor immediately at 100.4 degrees Fahrenheit or above. So call your care team right away, day or night. If nobody answers, go to the ER or call 911. Tell the person checking you in that you are on chemotherapy. Do not wait for morning.
One mismatch is worth naming. NCI's own infection page prints "fever of 100.5 °F (38 °C) or higher." Thirty-eight degrees Celsius is 100.4 degrees Fahrenheit, not 100.5. The gap is small, but two federal pages give different numbers. Sources word this threshold differently, so the figure a care team gives is the one that governs.
NCI adds a second point. Do not take aspirin, acetaminophen or ibuprofen for a fever without asking your doctor first. They can mask signs of a more serious problem.
If you are on chemotherapy, call your care team right away, day or night, for chills, a sore throat or new cough, burning when you urinate, or redness, swelling or drainage where an IV line or port goes in. Do this even if your temperature is normal. A normal temperature is not permission to wait. NCI and MedlinePlus list these as signs of infection.
Call 911 or go to the nearest emergency department if you have trouble breathing, are suddenly confused or hard to wake, or have black or tarry stool, vomit blood, or bleed heavily. Do not drive yourself.
Where the pet question sits in the rest of the plan
This is one piece of a wider infection picture during treatment, alongside infection and neutropenia and visitors and infection risk. Food handling follows the same logic and is covered in eating when your immune system is low.
The summary is short. Ask your care team about your pet. If you keep one, the chores can change hands.
This is general information. A care team's specific instructions for a specific treatment always take priority.
Sources

Common questions
Is it safe to be around pets during chemotherapy?
It depends. MedlinePlus lists cancer treatment among the conditions where some people are advised to give up pets. If you decide to keep one, it gives tips. The concern is infection passed from an animal to a person. Most of the tips point at feces, litter and tank water. Ask your care team what is right for you.
What pet tasks should be handed to someone else during chemo?
MedlinePlus advises against picking up pet waste, cleaning fish tanks and cleaning birdcages. Where a litter pan must be changed by the person in treatment, rubber gloves and a disposable face mask are advised, with disposable pan liners so the whole pan can be cleaned at each change.
Does a pet have to be rehomed during treatment?
That is a choice to make with your care team. MedlinePlus sets out precautions for keeping a dog, cat, bird, fish or reptile, including feeding only commercially prepared food, keeping a cat's nails short, and adopting animals older than one year rather than kittens or puppies.
What counts as a fever worth calling about?
MedlinePlus gives 100.4 degrees Fahrenheit (38 degrees Celsius) or higher as a sign of infection to report right away. NCI's infection page prints 100.5 degrees Fahrenheit alongside the same 38 degrees Celsius, which does not convert. The number a care team gives is the one that governs.
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Last updated: 2026-09-29Next planned review: 2028-07-14
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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