The short answer
The USPSTF is a scientifically independent, volunteer panel of national experts in prevention and evidence-based medicine, created in 1984. It reviews evidence on preventive services and grades them A, B, C, D or I. Its recommendations apply only to people with no signs or symptoms of the disease, and it does not consider cost when assigning a grade.
The Task Force is a scientifically independent, volunteer panel of national experts, established in 1984.
Since 1998, Congress has authorized AHRQ to convene it.
Its recommendations apply only to people who have no signs or symptoms of the specific disease.
Grades A and B mean offer or provide the service; C means offer selectively; D means discourage it.
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Where screening advice starts
This page explains who the U.S. Preventive Services Task Force is, what its letter grades mean, and how to use them with your clinician.
You may hear that colon cancer screening should start at a certain age, or that a scan is recommended for heavy smokers. That advice came from somewhere. Often it came from the U.S. Preventive Services Task Force.
The Task Force is a scientifically independent, volunteer panel of national experts in prevention and evidence-based medicine. It was established in 1984. Its job is to make evidence-based recommendations about clinical preventive services in order to improve health.
Its members come from preventive medicine and primary care. That includes internal medicine, family medicine, pediatrics, behavioral health, obstetrics and gynecology, and nursing. They serve as volunteers.
Since 1998, Congress has authorized the Agency for Healthcare Research and Quality to convene the Task Force. The panel remains scientifically independent in its judgments.
The grades, in plain language
The Task Force reviews the evidence on a service and gives it a letter. Each letter carries a suggestion for practice.
Grade A. The Task Force recommends the service. There is high certainty that the net benefit is substantial. Suggestion: offer or provide it.
Grade B. The Task Force recommends the service. There is high certainty that the net benefit is moderate, or moderate certainty that it is moderate to substantial. Suggestion: offer or provide it.
Grade C. The Task Force recommends selectively offering the service to individual patients based on professional judgment and patient preferences. There is at least moderate certainty that the net benefit is small. Suggestion: offer it for selected patients depending on individual circumstances.
Grade D. The Task Force recommends against the service. There is moderate or high certainty that it has no net benefit, or that the harms outweigh the benefits. Suggestion: discourage its use.
I statement. The current evidence is insufficient to assess the balance of benefits and harms. If the service is offered, patients should understand that uncertainty about benefits and harms.
Two features that explain a lot
The first is scope. The recommendations apply only to people who have no signs or symptoms of the specific disease, and they address primary care settings.
That single sentence resolves a lot of confusion. If you have a symptom such as a lump, bleeding or a persistent cough, do not wait for a screening schedule. Call your care team. The Task Force recommendations apply only to people with no signs or symptoms.
The second is cost. The Task Force does not consider costs when determining grades.
What the Task Force can do for you today
Its recommendations are published on its website or in peer-reviewed journals, and it submits annual reports to Congress identifying research gaps.
It can also give you better language for a conversation. Instead of asking whether you "should" get a test, you can ask what grade it carries and whether you fall inside the group the recommendation covers.
What the Task Force cannot do for you
It cannot tell you what to do. A grade is a population-level statement about people with no symptoms. You are a person with a history, a family, a risk level and your own preferences.
It does not treat anyone. It does not consider cost when determining grades, so a grade tells you nothing about what a test will cost you. Ask your plan about coverage.
A C grade means selectively offering the service based on professional judgment and patient preferences, so it is a decision to make with your clinician. An I statement means the evidence is insufficient to assess the balance of benefits and harms.
The takeaway
The Task Force makes recommendations for people without symptoms. It is not a substitute for advice from your clinician.
Bring that record to your next primary care visit and ask where you personally fit. That conversation, not the letter grade alone, is what turns a recommendation into a decision.

Common questions
Who sits on the Task Force?
Volunteer experts from preventive medicine and primary care, including internal medicine, family medicine, pediatrics, behavioral health, obstetrics and gynecology, and nursing.
What does a grade A mean?
The Task Force recommends the service, with high certainty that the net benefit is substantial. The suggestion for practice is to offer or provide it.
What is the difference between B and C?
A B grade means the service is recommended, with high certainty of moderate net benefit or moderate certainty of moderate to substantial benefit. A C grade means selectively offering it based on professional judgment and patient preferences, with at least moderate certainty that net benefit is small.
Why would a test get a D grade?
Because there is moderate or high certainty that it has no net benefit, or that its harms outweigh its benefits. The suggestion is to discourage its use.
What does an I statement mean for me?
It means current evidence is not enough to judge the balance of benefits and harms. If the service is offered anyway, you should understand that uncertainty.
Do the recommendations apply if I already have cancer?
No. They apply only to people who have no signs or symptoms of the specific disease, in primary care settings. If you have symptoms, call your care team; the recommendations are not about testing after a diagnosis or a symptom.
Does the Task Force weigh what a test costs?
No. It states that it does not consider costs when determining grades.
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Sources last checked: 2026-09-03 what this meansLast updated: 2026-10-16Next planned review: 2027-09-03
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Editorial review complete — This page completed Cancer Explained's editorial checks (sources, safety, plain language, duplication). It has not been reviewed by a physician or other healthcare professional.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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