The short answer
NCCIH is one of the 27 Institutes, Centers, and Offices that make up the National Institutes of Health. Its stated mission is to determine, through rigorous scientific investigation, the fundamental science, usefulness, and safety of complementary and integrative health approaches. It is a research agency, so it can help you find plain-language summaries of what the evidence shows. It does not treat patients, endorse products, or tell you what to take.
NCCIH is a federal research center inside the National Institutes of Health, established in October 1998.
Its mission is to study the fundamental science, usefulness, and safety of complementary and integrative health approaches.
NCCIH distinguishes complementary (used together with conventional medicine) from alternative (used in place of it) and integrative health (both brought together in a coordinated way).
NCCIH notes that research on dietary supplements has often found products did not work for the conditions studied, and that more is needed on safety and interactions with medicines.
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The full explanation.
A research center, not a recommendation service
The National Center for Complementary and Integrative Health is one of the 27 Institutes, Centers, and Offices that make up the National Institutes of Health. It was established in October 1998. It is the federal government's lead agency for scientific research on health practices that sit outside conventional medicine.
That last sentence matters more than it looks. NCCIH studies these approaches. Studying something is not the same as recommending it. A study can find that a practice helps. It can also find that a practice does nothing, or that it causes harm. All three results are useful science.
NCCIH states its mission plainly. It exists to determine, through rigorous scientific investigation, the fundamental science, usefulness, and safety of complementary and integrative health approaches. Note that safety sits in the mission alongside usefulness. The agency is not only asking whether something works. It is also asking whether it hurts.
The words the agency uses
NCCIH separates three terms, and the difference is worth learning because people use them loosely.
- Complementary means used together with conventional medicine.
- Alternative means used in place of conventional medicine.
- Integrative health means conventional and complementary approaches brought together in a coordinated way, with attention to the whole person.
The gap between the first and the second is the important one. Adding a gentle practice alongside your oncology care is a different decision from replacing that care. NCCIH also notes that in a national survey, most American adults who used non-mainstream approaches continued their conventional care as well.
What NCCIH can do for you today
Three things, really.
It can give you plain-language summaries. NCCIH publishes pages that walk through what the research has actually found on specific practices and products, in ordinary English, without a sales pitch attached.
It can tell you where the evidence is thin. This is its most useful service. NCCIH is direct that research on dietary supplements has often found the products did not work for the conditions studied. It also says more research is needed on how supplements act in the human body, on their safety, and on their potential interactions with medicines.
It can help you ask better questions. Once you know what has and has not been studied, the conversation with your oncology team changes. You stop asking whether something is good. You start asking whether it is safe for you.
It is a federal agency, so all of this is free to read.
What NCCIH cannot do
It cannot treat you. NCCIH is not a clinic. It does not manage anyone's cancer care.
It cannot endorse a product or a brand. There is no NCCIH seal of approval, and anyone claiming one is misrepresenting the agency. If a supplement bottle or a website hints that NCCIH backs it, that is marketing, not government.
It cannot answer questions about your own body. NCCIH says directly that its material is not intended to substitute for the medical expertise and advice of your own health care providers. It does not know your diagnosis, your drugs, your doses, your liver and kidney function, or your surgery date.
And it cannot resolve uncertainty that the science has not resolved yet. When the honest answer is that nobody knows, NCCIH will say so. That is the agency working correctly, even though it is frustrating to read.
Why "natural" is not a safety claim
This is the part that deserves the most care during cancer treatment.
Cancer treatments are powerful, and many are processed by the same liver pathways that handle herbs and supplements. A product can change how much of a drug ends up in your blood. Too little and the treatment underperforms. Too much and the side effects get worse. Some products affect bleeding, which matters before surgery or a biopsy. Some can affect blood counts or liver tests, which can muddy the results your team relies on.
None of that is visible from the label. A product can be plant-based, sold in a pharmacy, recommended by someone kind who loves you, and still be a bad idea this month.
The one habit worth building
Bring the actual containers to your appointment. Not a list from memory. The bottles, the tea, the powder, the drops.
Let your oncology team read the labels. Ask whether anything needs to stop, whether anything needs to pause around treatment days, and whether anything should be watched with a blood test. Ask whether the hospital has a supportive care or integrative medicine service, because many cancer centers do.
That is the whole system working as intended. NCCIH does the research and publishes what it finds. Your care team applies it to you.
Words to know
Tap any term to see what it means.

Common questions
Does NCCIH recommend any complementary approach for cancer?
No. NCCIH is a research agency. Its role is to study whether approaches work and whether they are safe, and to publish what the evidence shows. It does not issue treatment recommendations for individual patients, and a page existing on its site is not an endorsement.
Is something safe just because it is natural or sold without a prescription?
No. NCCIH points out that much remains unknown about how supplements act in the human body, including their safety and their potential interactions with medicines. Natural is not the same as harmless, especially during cancer treatment.
What is the difference between complementary and alternative?
NCCIH defines complementary as used together with conventional medicine, and alternative as used in place of conventional medicine. Integrative health brings conventional and complementary approaches together in a coordinated way.
Can NCCIH tell me whether a supplement will interact with my chemotherapy?
It can point you to what the published research shows in general. It cannot look at your specific drugs, doses, kidney and liver function, or timing. Only your oncology team can do that, so bring the actual bottle to them.
Does NCCIH treat patients?
No. It funds and conducts research and shares information. Some NIH studies enroll volunteers, but NCCIH is not a clinic you can go to for care.
Is NCCIH information free?
Yes. It is a federal agency and its public information pages are free to read.
Questions to ask your doctor
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Plain-language explanation of the published sources cited on this page. AI-assisted, source-checked, not clinician-reviewed.
Sources last checked: 2026-09-03 what this meansLast updated: 2026-09-03Next planned review: 2027-09-03
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Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
How this page was created
Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Editorial review complete — This page completed Cancer Explained's editorial checks (sources, safety, plain language, duplication). It has not been reviewed by a physician or other healthcare professional.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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