The short answer
Cancer treatment can weaken the immune system, so foods that may carry germs become riskier than usual. MedlinePlus advises avoiding raw fish such as sushi and sashimi, raw shellfish, soft and unpasteurised cheeses, runny eggs and raw sprouts, and gives specific cooking temperatures.
MedlinePlus says not to eat raw fish such as sushi or sashimi, raw oysters or any other raw shellfish.
Egg yolks and whites should be cooked solid, and uncooked tofu is not advised.
Soft cheeses such as Brie, Camembert, blue-veined varieties and Mexican-style fresh cheeses are on the avoid list.
Only pasteurised dairy products should be eaten, and unpasteurised juices avoided.
On this page
Choose how you want to read this
The whole article, with every detail and caution.
This page is for people on chemotherapy or other treatment that weakens the immune system. It explains which raw and risky foods to avoid, safe cooking temperatures, and what to do if you slip up.
This is a germ rule, not a diet
The restrictions handed out at the start of chemotherapy get mistaken for nutrition advice. They are not. Nobody is claiming sushi is unhealthy.
The FDA sets out the reasoning. Cancer therapy such as radiation, chemotherapy and other medicines may weaken the immune system. That makes patients more open to infections like foodborne illnesses. Cancer that spreads to bone marrow weakens immune function directly.
So the foods on the avoid list are the ones most likely to carry live germs. Normally your immune system deals with them quietly. During treatment, it may not.
The list itself
MedlinePlus guidance on safe eating during cancer treatment names specific items.
Raw proteins
- Do not eat raw fish, such as sushi or sashimi, raw oysters, or any other raw shellfish
- Avoid runny eggs — yolks and whites should be cooked solid
- Do not eat uncooked tofu
Dairy
- Avoid soft cheeses such as Brie, Camembert and blue-veined varieties
- Avoid Mexican-style fresh cheeses including queso blanco fresco and cotija
- Consume only pasteurized dairy products
Other items to avoid
- Raw vegetable sprouts such as alfalfa and mung bean
- Raw honey, and sweets with creamy fillings
- Fresh salsa and refrigerated salad dressings from grocery stores
- Unpasteurized juices
The deli counter shows up twice on this list for a reason. Those foods are ready to eat. Many hands have touched them. And they sit at fridge temperature. That is exactly the situation the guidance is built around.
Cooking, washing and temperatures
MedlinePlus gives figures worth writing on a card. Stick the card inside a cupboard door.
- Poultry and casseroles: 165 °F (74 °C)
- Beef, lamb, pork and venison: 160 °F (71 °C)
- Tofu: cook for at least 5 minutes
For fresh produce, the instruction is simple. Wash all raw fruits, vegetables and fresh herbs under cold running water.
A cheap food thermometer removes the guesswork from the first two. Judging doneness by eye is the sort of rough guess this guidance is meant to replace.
Cooked properly is the theme. Most of what is banned raw is fine once heat has done its job.
Eating out without giving it up
MedlinePlus does not ask you to stop going out. It asks you to choose differently.
Its advice is to avoid salad bars, buffets, sidewalk vendors, potlucks and delis. Request food prepared fresh. Use single-serving salsa and condiments rather than shared containers.
The common thread is food that has been sitting out, handled again and again, or shared. A dish cooked to order and brought straight to the table is a very different thing from a tray under a heat lamp for an hour.
How long does this last?
That depends on you. It is the question to take to your clinic. Different treatments carry different levels of risk. Immune recovery also varies a lot between people and regimens.
Ask directly how strict your team wants you to be. Ask whether the rules tighten during certain parts of your cycle. And ask when they can be relaxed. Guidelines written for everyone have to be cautious. Your team can tell you where you sit within them.
If something goes wrong
Eating something from the avoid list happens. A slice of cake with a soft cheese filling. A sandwich made by someone who did not know. Panicking helps nobody.
Watch for signs of infection and report them promptly. CDC says infections during cancer treatment can be life threatening and require urgent medical attention. It says to call your doctor right away for a temperature of 100.4 °F (38 °C) or higher, even in the middle of the night, because fever may be the only sign of infection. CDC also says to take your temperature whenever you feel warm, flushed, chilled or unwell. If you go to the emergency room, say that you are on chemotherapy.
Call your team. Do not wait to see how the night goes. Do not take fever medicine before you have spoken to your team.

Common questions
Why does this suddenly matter?
The FDA explains that cancer therapies such as radiation, chemotherapy and other medicines may weaken the immune system, making patients more vulnerable to infections including foodborne illness. It adds that cancer spreading to bone marrow directly affects immune function.
Is it really all raw fish?
MedlinePlus is specific: do not eat raw fish, such as sushi or sashimi, raw oysters, or any other raw shellfish. Cooked fish dishes are a different matter — ask your team about your own restrictions.
What about cheese?
MedlinePlus advises avoiding soft cheeses including Brie, Camembert and blue-veined varieties, and Mexican-style fresh cheeses such as queso blanco fresco and cotija. It says to consume only pasteurised dairy products.
Can I eat out at all?
MedlinePlus advises avoiding salad bars, buffets, potlucks and delis, requesting freshly prepared food, and using single-serving condiments only. It does not say to stop eating out entirely.
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Fever of 100.4°F (38°C) or higher during chemo, severe pain, or trouble breathing: call your cancer care team right away, day or night. Call 911 for an emergency.
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Sources last checked: 2026-08-11 what this meansLast updated: 2026-08-20Next planned review: 2027-08-11
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Cancer Explained does not originate medical claims. Every page restates guidance already published by the National Cancer Institute, the CDC, the USPSTF and the FDA, in plain language, with the source cited so you can check the original yourself. AI does the translating and organizing; automated checks test claims, citations, clarity and safety before anything publishes, and this is translation and navigation, not clinical judgment. Nothing here is personal medical advice, and no page can account for your particular situation.
Editorial status: Source checked — This page was written with AI assistance and then compared with the sources listed on it, looking for statements those sources do not back up. That check is not a sentence-by-sentence record and can miss errors. It is not a medical review, and it does not confirm the page is complete or right for your situation.
Human medical review: not completed. Pages here are not signed off by a clinician before they publish. That is not an oversight we are quietly working around: we restate published guidance and cite it, so the authority belongs to the source rather than to us, and every page names where its claims come from — you can verify us instead of trusting us. Where a volunteer clinician has reviewed a page, their name and credentials appear on it; where no name appears, no clinician has checked it. We are glad to have reviewers and are recruiting them, and we do not hold pages back waiting for one. Use this site to understand your situation and to ask better questions of the people treating you.
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