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🛡️ The causes we can do something about

Vaccines That Prevent Cancer

Two ordinary vaccines prevent infections that cause cancer. This is the closest thing to a cancer vaccine that exists, and it already sits in every pediatrician's fridge.

The idea

Some cancers start with an infection. Prevent the infection, and you prevent the cancers it would have caused years or decades later.

That is not a theory. It is two routine vaccines that already exist.

HPV

HPV is a very common virus. Most infections clear up on their own and cause nothing at all. Some do not clear. Those are the ones that can lead to cancer, many years later.

NCI names six cancers caused by HPV:

  • Cervix
  • Throat, the middle part behind the mouth
  • Anus
  • Penis
  • Vagina
  • Vulva

Three of those happen in men. So this was never a girls-only issue.

NCI reports that each year in the US, there are over 47,900 new cancers in the parts of the body where HPV is often found. NCI estimates HPV causes about 37,800 of them. NCI also estimates the vaccine prevents up to 90 percent of the cancers HPV causes, plus genital warts.

The schedule, per CDC

  • The routine ages are 11 and 12, with two doses given 6 to 12 months apart
  • Shots can start as early as age 9
  • If the series starts after age 15, three doses are needed
  • Gardasil-9 is the only HPV vaccine given in the US. It covers nine types of the virus

CDC calls the common side effects mild: a sore arm, a fever, a headache. Studies show protection lasting about 12 years so far.

Is it working?

Yes, and CDC has the numbers. Since shots began in 2006:

  • Infections with the HPV types behind most HPV cancers are down 88 percent among teen girls
  • They are down 81 percent among young adult women
  • Cervical precancers are down 40 percent among women who got the vaccine

Hepatitis B

CDC says a vaccine is the best way to prevent hepatitis B. CDC also says that if a long-term hepatitis B infection goes untreated, it can cause liver damage, scarring of the liver, liver cancer, and death.

The chain is worth stating exactly, because it is easy to overstate. The vaccine prevents the infection. And a long-term infection, left untreated, is one of the things that can lead to liver cancer.

CDC recommends the vaccine for:

  • All infants
  • All children and teens under 19 who have not had it
  • Adults aged 19 to 59
  • Adults 60 and over who have risk factors

Hepatitis C

Hepatitis C is a different case. CDC says that here too, a long-term infection left untreated can cause liver damage, scarring, and liver cancer.

What makes it different is that it can be cured. CDC says treatments can cure most people within 8 to 12 weeks. Which makes finding it the whole game.

CDC recommends that:

  • All adults 18 and over get tested at least once in their life
  • Pregnant women get tested during each pregnancy
  • People with certain risks get tested more often. That includes people who inject drugs, people with HIV, people with abnormal liver tests, and anyone who had a blood transfusion before 1992

If you have never had that one-time test, it is a fair thing to ask about at your next visit.

The numbers

These describe groups of people, not any one person. Each one names the agency it came from and the years it covers.

US cancers each year estimated to be caused by HPV
About 37,800
NCI
Share of HPV-caused cancers and genital warts the vaccine is estimated to prevent
Up to 90 percent
NCI
Drop in cancer-causing HPV infections among teen girls since vaccination began in 2006
88 percent
CDC
Drop in cancer-causing HPV infections among young adult women
81 percent
CDC
Drop in cervical precancers among vaccinated women
40 percent
CDC
Time to cure most hepatitis C with treatment
8 to 12 weeks
CDC

What people get wrong

  • Myth: The HPV vaccine is only for girls.

    What the evidence says: NCI lists six cancers caused by HPV: anal, cervical, oropharyngeal, penile, vaginal, and vulvar. Three of those can occur in men. CDC's routine recommendation is for children at ages 11 to 12, not girls at 11 to 12.

    Read the source
  • Myth: It is too late for me, I am past the recommended age.

    What the evidence says: The schedule changes rather than closing. CDC says vaccination can begin at age 9, that the routine age is 11 to 12 with two doses six to twelve months apart, and that a series started after age 15 needs three doses. Whether it is useful for a particular adult is a conversation with a clinician.

    Read the source
  • Myth: A hepatitis vaccine has nothing to do with cancer.

    What the evidence says: It has a lot to do with liver cancer, through one clear chain. CDC states that vaccination is the best way to prevent hepatitis B, and that left untreated, chronic hepatitis B can cause serious health problems including liver damage, cirrhosis, and liver cancer.

    Read the source

Words on this page

HPV
Human papillomavirus, a very common virus spread by skin-to-skin and sexual contact. Some types cause cancer years later.
Cervix
The lower part of the uterus, at the top of the vagina. Cervical cancer is the most well known HPV cancer.
Oropharyngeal
The middle part of the throat, behind the mouth. HPV causes cancer here too, in men as well as women.
Chronic
Long-lasting. A chronic hepatitis infection is one the body did not clear.

If you want more detail

These pages are longer and go further into the same topic.

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