Skip to main content
Cancer Explained

Disponible en español: Cómo se administra la quimioterapia

Beginner 6 min readSource verified

How Chemotherapy Is Given

A plain-language guide to the different ways chemotherapy can be given, from pills to IVs, ports, and pumps. Based on National Cancer Institute resources.

AI-assisted and source verified. Not reviewed by a healthcare professional unless specifically stated.

Sources last checked: 2026-07-14Last updated: 2026-07-14Next planned review: 2027-07-14

How this page was created

Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

Editorial status — Source verified. This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

General education — varies by person. Answers genuinely differ between people. This page explains what commonly varies and points you to your care team for your situation.

Human medical review: not completed. At this time, most Cancer Explained content has not been reviewed by a physician or other healthcare professional. Pages with documented human medical review identify the reviewer, credentials, and review date directly.

Our editorial processHow we use AIReport an error

NCI source

National Cancer Institute

The short answer

Chemotherapy can be given in many ways, such as pills you swallow, an injection, or most often through an IV in a vein. Some people receive it through a catheter, a port, or a pump. The method depends on your cancer and the drugs used.

  • Chemotherapy is given in several ways, including by mouth, injection, or through a vein (IV).

  • IV chemotherapy is the most common method and can be given through a thin needle, a catheter, a port, or a pump.

  • A catheter is a soft tube placed in a large vein; a port is a small disc placed under the skin.

  • Watch for signs of infection around a catheter or port and tell your care team right away.

Choose how you want to understand this

The full explanation.

The simple version

Chemotherapy (also called chemo) uses drugs to kill cancer cells or slow their growth. But there is no single way to give it. The method your team chooses depends on your type of cancer, the drugs being used, and where the cancer is in your body.

Chemotherapy can reach your body in several different ways, and your team picks the one that fits your treatment.

The common ways chemotherapy is given

Chemotherapy may be given in many ways. Some common ones are:

  • Oral: pills, capsules, or liquids that you swallow.
  • Intravenous (IV): the drug goes directly into a vein.
  • Injection: a shot given into a muscle in your arm, thigh, or hip, or just under the skin in the fatty part of your arm, leg, or belly.
  • Intrathecal: injected into the space between the layers of tissue that cover the brain and spinal cord.
  • Intraperitoneal (IP): placed directly into the peritoneal cavity, the area that holds organs such as the intestines, stomach, and liver.
  • Intra-arterial (IA): injected directly into the artery that leads to the cancer.
  • Topical: a cream that you rub onto your skin.

Of all these methods, chemotherapy is most often given by IV.

A closer look at IV chemotherapy

For IV chemotherapy, a nurse places a thin needle in a vein on your hand or lower arm. The nurse puts the needle in at the start of each treatment and removes it when treatment is over.

IV chemotherapy can also be given through a catheter or a port, and sometimes with the help of a pump.

A catheter. A catheter is a thin, soft tube. A doctor or nurse places one end in a large vein, often in your chest area, while the other end stays outside your body. Most catheters stay in place until you finish your chemotherapy. Catheters can also be used to give other drugs and to draw blood.

A port. A port is a small, round disc that a surgeon places under your skin during minor surgery. It is put in before your treatment begins and stays until you finish. A catheter connects the port to a large vein, most often in your chest. Your nurse can insert a needle into the port to give chemotherapy or draw blood. This needle can be left in place for treatments given over more than one day.

A pump. Pumps are often attached to catheters or ports. They control how much and how fast chemotherapy goes in, which can let you receive treatment outside of the hospital. External pumps stay outside your body. Internal pumps are placed under your skin during surgery.

Watching for infection. With a catheter or a port, be sure to watch for signs of infection around the area and tell your care team if you notice any.

How your team chooses your drugs

There are many different chemotherapy drugs. Which ones are part of your plan depends mostly on:

  • the type of cancer you have and how advanced it is
  • whether you have had chemotherapy before
  • whether you have other health problems, such as diabetes or heart disease

Your care team matches both the drugs and the method to your situation.

Where you go for chemotherapy

You may receive chemotherapy during a hospital stay, at home, or as an outpatient at a doctor's office, clinic, or hospital. Outpatient means you do not stay overnight.

No matter where you go, your doctor and nurse will watch for side effects and help you manage them. If you receive chemotherapy at home through a pump, your team will teach you and your caregivers what to do and what to watch for.

Words to know

Tap any term to see what it means.

Browse the full glossary →

Common questions

What are the main ways chemotherapy can be given?

Chemotherapy can be given as pills, capsules, or liquids you swallow; as an injection; or directly into a vein through an IV. It can also be placed into other areas, such as the space around the brain and spinal cord or the peritoneal cavity. It is most often given through an IV.

What is the difference between a catheter and a port?

A catheter is a thin, soft tube placed in a large vein, often in the chest, with one end staying outside the body. A port is a small, round disc placed under the skin during minor surgery and connected to a large vein. Both can be used to give chemotherapy and draw blood.

What is a chemotherapy pump?

A pump is often attached to a catheter or port. It controls how much and how fast chemotherapy goes in, which can let you receive chemotherapy outside the hospital. Pumps can be external (outside the body) or internal (placed under the skin during surgery).

Does IV chemotherapy hurt?

For IV chemotherapy, a nurse places a thin needle in a vein in your hand or lower arm at the start of each treatment and removes it when treatment is over. Your care team can help you manage any discomfort.

Why would someone need a port instead of a regular IV?

A port lets a needle be inserted to give chemotherapy or draw blood, and the needle can be left in place for treatments given over more than one day. A surgeon places the port before treatment begins, and it stays until treatment is finished.

Where will I go to receive chemotherapy?

You may receive chemotherapy during a hospital stay, at home, or as an outpatient at a doctor's office, clinic, or hospital. Outpatient means you do not stay overnight. Your doctor and nurse will watch for side effects wherever you go.

Questions to ask your doctor

Being prepared helps you get the most out of your appointments. Save or print these questions.

Open my question list

Tap a question to save it to your list (kept on this device).

Quick quiz

Test your knowledge

0 of 4 answered

  1. Q1.According to this article, what is the most common way chemotherapy is given?
  2. Q2.According to this article, what is a port?
  3. Q3.According to this article, what does a chemotherapy pump do?
  4. Q4.According to this article, what should you watch for around a catheter or port?

This quiz checks understanding of educational content only. It is not medical advice. Open this quiz on its own page.

How this page was created

Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

Editorial status: Source verified This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

Human medical review: not completed. At this time, most Cancer Explained content has not been reviewed by a physician or other healthcare professional. Pages with documented human medical review identify the reviewer, credentials, and review date directly.

Read more about our editorial process, our use of AI, and our corrections policy.

Spotted a problem? Report an error — a factual mistake, broken or outdated source, confusing wording, or anything that seems unsafe. Please do not include names, medical record numbers, dates of birth, addresses, or other identifying medical information in your report.

After using this page, do you understand what to do next?

Anonymous — we only record the answer, never who gave it.

Related learning map

How this explanation connects to 15 other things you can explore — related topics, terms, questions, practice, and its NCI source.

How Chemotherapy Is Given