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Basal and Squamous Cell Skin Cancer: Treatment Options

How to discuss basal and squamous cell skin cancer treatment goals, benefits, risks, specialists, supportive care, and clinical trials.

This is general education — it cannot tell you what to do in your situation.

Instructions and urgent-contact thresholds vary by treatment and care team. If you are in treatment, follow the instructions your oncology team gave you, and contact them about any new or worsening symptom. If you think you may be having a medical emergency, call your local emergency number.

AI-assisted and source verified. Not reviewed by a healthcare professional unless specifically stated.

Sources last checked: 2026-07-22Last updated: 2026-07-22Next planned review: 2027-01-22

How this page was created

Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

Editorial status — Source verified. This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

High-risk topic — talk to your care team. This topic can involve urgent, individual medical decisions. This page is general education only: it cannot tell you whether your situation is an emergency or what you personally should do. Follow your oncology team's instructions and contact them for individual guidance.

Human medical review: not completed. At this time, most Cancer Explained content has not been reviewed by a physician or other healthcare professional. Pages with documented human medical review identify the reviewer, credentials, and review date directly.

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NCI source

National Cancer Institute — Basal Cell and Cutaneous Squamous Cell Skin Cancer

Basal and Squamous Cell Skin Cancer: Treatment Options

The short answer

Treatment may involve local procedures, surgery, radiation, medicines for selected advanced disease, and clinical trials, but the right discussion depends on type, size, depth, location, recurrence, spread, and immune status.

  • Treatment categories may include local procedures, surgery, radiation, medicines for selected advanced disease, and clinical trials.

  • The plan depends on type, size, depth, location, recurrence, spread, and immune status.

  • The goal of treatment should be stated clearly.

  • Supportive and rehabilitation needs belong in the plan from the beginning.

Choose how you want to understand this

The full explanation.

Start with the goal

Ask the team to state the treatment goal in one sentence. Depending on the situation, the goal may be to remove or destroy cancer, reduce recurrence risk, control disease, relieve symptoms, preserve function, or learn through a clinical trial.

Options that may enter the conversation

Broad categories may include local procedures, surgery, radiation, medicines for selected advanced disease, and clinical trials. A category is not a recommendation. The plan depends on type, size, depth, location, recurrence, spread, and immune status.

For each option, ask about expected benefit, uncertainty, important short- and long-term harms, time in treatment, monitoring, and alternatives. Numbers should describe people similar to you whenever possible.

Sequence and specialist care

Ask why the treatments are ordered in a particular sequence and which specialists need to coordinate. For an uncommon cancer, ask how often the center treats it and whether a multidisciplinary review would add value.

Supportive care is part of treatment

Discuss symptom control, nutrition, rehabilitation, emotional support, fertility or sexual health, transport, work, and caregiver capacity before problems become emergencies. Palliative care can support symptoms and goals at any stage and is not limited to hospice.

Make the decision visible

Write a short comparison with rows for goal, benefit, harms, logistics, alternatives, and unknowns. Ask what happens if you take more time, choose another option, or choose no cancer-directed treatment.

Do not start, stop, or change cancer treatment or supportive medicines from this page. Use the individualized instructions from the treating team.

Words to know

Tap any term to see what it means.

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Common questions

Is there one standard treatment for everyone?

No. The exact diagnosis, extent, health, goals, and available expertise shape the plan.

What should I compare?

Compare treatment goal, chance and size of benefit, important harms, time burden, alternatives, and what happens without the option.

When should I ask about a clinical trial?

It is reasonable to ask at diagnosis, before a major treatment change, and if standard options are limited.

Does a second opinion delay care?

Ask how much time is medically safe. Many reviews can happen quickly, but some fast-moving situations require urgent coordination.

Questions to ask your doctor

Being prepared helps you get the most out of your appointments. Save or print these questions.

Open my question list

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Your next step

Turn this guide into a short list for your care team.

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Contact your oncology team

Locate after-hours contact numbers, portal messages, or urgent triage phone lines.

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Get one-on-one help with appointments, logistics, translation, and care coordination.

Find a genetic counselor

Discuss inherited mutation risk, family history, and genetic testing options.

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Access emotional counseling, family support groups, and mental health resources.

Find a financial navigator

Locate copay assistance foundations, grant programs, and lodging/travel support.

Find a clinical-trial specialist

Search matching studies and speak with NCI trial information specialists.

Get urgent help

Immediate emergency guidance for fever (>100.4°F during chemo), severe pain, or shortness of breath.

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How this page was created

Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

Editorial status: Source verified This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

Human medical review: not completed. At this time, most Cancer Explained content has not been reviewed by a physician or other healthcare professional. Pages with documented human medical review identify the reviewer, credentials, and review date directly.

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Related learning map

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Basal and Squamous Cell Skin Cancer: Treatment Options