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External Beam Radiation Therapy

A plain-language guide to external beam radiation therapy — how a machine aims radiation at cancer, what a treatment session is like, and why it does not make you radioactive. Based on National Cancer Institute resources.

AI-assisted and source verified. Not reviewed by a healthcare professional unless specifically stated.

Sources last checked: 2026-07-14Last updated: 2026-07-14Next planned review: 2027-07-14

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Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

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National Cancer Institute

The short answer

External beam radiation therapy uses a machine to aim radiation at a specific part of the body. Most people have short treatments once a day, five days a week, for several weeks. It is painless during the session and does not make you radioactive.

  • External beam radiation comes from a machine that aims radiation at your cancer from outside the body.

  • It is a local treatment, meaning it treats only the specific part of the body with cancer.

  • Most people have treatment once a day, five days a week, over several weeks.

  • A planning session called simulation maps your treatment area, sometimes using tiny skin marks or a body mold.

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The full explanation.

The simple version

External beam radiation therapy comes from a machine that aims radiation at your cancer. It is a local treatment, which means it treats a specific part of your body. For example, if you have cancer in your lung, you will have radiation only to your chest, not your whole body.

It is used to treat many types of cancer.

The radiation comes from a machine outside your body and is aimed carefully at the cancer.

How it targets the cancer

There are many types of external beam radiation therapy, but they all share one goal: to deliver the highest prescribed dose of radiation to the tumor while sparing the healthy tissue around it. Each type uses a computer to study images of the tumor and calculate the most precise dose and path possible.

Some common types include 3-D conformal radiation therapy, which shapes the beams to the tumor from many directions, and intensity-modulated radiation therapy (IMRT), which uses many smaller beams and can change their strength. Image-guided radiation therapy (IGRT) uses scans during treatment to adjust for changes in the tumor's size and location. Other approaches, such as stereotactic radiosurgery, focus high-energy beams on small tumors with well-defined edges.

What happens before your first treatment

You will have a 1- to 2-hour meeting with your doctor or nurse before you begin. You will have a physical exam, talk about your medical history, and maybe have imaging tests. Your team will discuss the treatment, its benefits and side effects, and how to care for yourself. You can then choose whether to have it.

If you decide to go ahead, you will have a planning session called simulation. During simulation:

  • A radiation oncologist and radiation therapist figure out your treatment area while you lie very still and have x-rays or scans.
  • The therapist may tattoo or draw small dots of colored ink on your skin to mark the area. These help make sure you are in exactly the same position for every treatment. Tattooed dots are about the size of a freckle and are permanent; ink markings fade over time.
  • A body mold may be made to keep you from moving during treatment. If you are getting radiation to the head and neck, you may be fitted for a mask that keeps your head still.

What a treatment session is like

Most people get external beam radiation therapy as an outpatient, meaning you do not stay overnight.

At each session, you may change into a gown, then lie on a treatment table or sit in a special chair. The room will be cool. You may see harmless colored lights that help the therapist position you. You will need to stay very still so the radiation goes to the exact same place each time. The radiation itself takes about 1 to 5 minutes, and you can breathe normally.

The radiation therapist leaves the room just before treatment begins and controls the machine from nearby. They watch you on a screen or through a window and talk with you through a speaker. Tell them if you feel sick or uncomfortable — they can stop the machine at any time. You will hear and see the machine move, but you will not feel, hear, see, or smell the radiation. Most visits last 30 minutes to an hour, with most of that time spent getting you into position.

How often and for how long

Most people have treatment once a day, five days a week, Monday through Friday. Radiation is given in a series of treatments to let healthy cells recover and to make the radiation more effective. The span from your first treatment to your last is called a course of treatment. How many weeks you need depends on the type of cancer, the goal of treatment, the radiation dose, and the schedule.

It will not make you radioactive

People often wonder if they will be radioactive during treatment. External beam radiation therapy will not make you radioactive. You may safely be around other people, even pregnant women, babies, and young children.

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Common questions

What is external beam radiation therapy?

External beam radiation therapy comes from a machine that aims radiation at your cancer. It is a local treatment, which means it treats a specific part of your body. For example, if you have lung cancer, you would have radiation only to your chest, not your whole body.

How often will I have treatment?

Most people have external beam radiation therapy once a day, five days a week, Monday through Friday. Radiation is given in a series of treatments to allow healthy cells to recover and to make the radiation more effective. How many weeks depends on your cancer, the goal of treatment, and the radiation dose and schedule.

What happens at the planning session?

Before treatment you have a session called simulation. A radiation oncologist and radiation therapist map your treatment area while you lie still and have x-rays or scans. They may make small ink marks or tattoos on your skin, and sometimes a body mold or face mask is made to help you stay in the same position each time.

Does radiation therapy hurt during the session?

You will not feel, hear, see, or smell the radiation. You lie still for about 1 to 5 minutes while the machine delivers treatment, and you can breathe normally. Most visits last 30 minutes to an hour, with most of that time spent placing you in the correct position.

Will external beam radiation make me radioactive?

No. External beam radiation therapy will not make you radioactive. You may safely be around other people, including pregnant women, babies, and young children.

What should I wear to treatment?

Wear comfortable clothes made of soft fabric that are easy to take off, since you may need to expose the treatment area or change into a gown. Avoid tight clothing near the treatment area, and do not wear jewelry, adhesive bandages, or powder there.

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How this page was created

Cancer Explained uses AI to organize and translate information from the authoritative sources cited on each page. Automated checks review claims, citations, clarity, duplication, and potential safety concerns before publication. Our content is not currently reviewed by physicians unless a specific qualified reviewer is named on the page. Cancer Explained provides general education and should not replace advice from your healthcare team.

Editorial status: Source verified This page was created with AI assistance and checked against the sources listed on it. Source checking is not a medical review.

Human medical review: not completed. At this time, most Cancer Explained content has not been reviewed by a physician or other healthcare professional. Pages with documented human medical review identify the reviewer, credentials, and review date directly.

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External Beam Radiation Therapy