Constipation and Cancer Treatment
A plain-language look at why constipation happens during cancer treatment and the ways people can prevent and relieve it, based on National Cancer Institute resources.
Source: National Cancer Institute · NCI reviewed 2025-05-16 · Verified 2026-07-02
The 30-second version
Constipation is when stool moves slowly through the large intestine, becoming dry and hard. It can be a side effect of cancer treatment, certain medicines, or less activity and diet changes. Drinking fluids, staying active, and medicines your doctor recommends can help. Tell your team early, because untreated constipation can lead to serious problems.
Key takeaways
- Constipation means stool moves slowly through the large intestine and becomes dry and hard.
- It can be caused by some chemotherapy, opioid pain medicines and other drugs, and being less active or eating differently.
- Signs include two or fewer bowel movements in a week, hard stool, straining, and belly pain or bloating.
- Drinking plenty of fluids, gentle daily activity, and eating at regular times can help prevent and ease it.
- Only use laxatives, suppositories, or enemas that your doctor recommends.
- Long-term constipation can lead to fecal impaction, a serious condition that needs immediate medical care.
Choose how you want to understand this
The full explanation.
What constipation is
Constipation is the slow movement of stool (poop) through the large intestine, the long tube that carries waste out of your body. The longer stool takes to move through, the more fluid it loses and the drier and harder it becomes.
If you are constipated, you may be unable to have a bowel movement, need to push harder than usual, or have fewer bowel movements than normal. Constipation may last a short time, or it may be chronic and last for a long time.
Tell your doctor if you have constipation. They can recommend medicines and other ways to treat it. Treating it early also helps prevent more serious problems.
Signs and symptoms
Signs and symptoms of constipation include:
- having two or fewer bowel movements in one week
- dry, hard, or lumpy stool
- pain during a bowel movement
- difficulty having a bowel movement
- stomach pain or cramps
- feeling bloated or nauseous
What causes it
Constipation in people with cancer may be caused by:
- Certain types of cancer. Constipation can be a sign of cancers that press on organs in the belly, block the movement of stool, or affect the nerves connected to the bowel.
- Cancer treatments such as chemotherapy. Constipation is a common side effect of some types of chemotherapy.
- Medicines. Many medicines can cause constipation, including opioid pain medicines, anti-anxiety drugs, anti-nausea drugs, and diuretics.
- Lifestyle and diet changes. During treatment you may have less energy for exercise, and your appetite and diet may change. Being less active and eating differently can lead to constipation.
How it is diagnosed
Finding the cause helps you get relief and avoid serious problems. Your doctor will do a physical exam, looking at and feeling your belly and listening to your bowel sounds. They may ask how often you have bowel movements, when your last one was and what it was like, and whether you have fever, cramps, pain, or bloating.
Sometimes your doctor may do other tests, such as a digital rectal exam (feeling inside the lower rectum with a gloved finger) or an x-ray of the belly, which can show a tumor or impacted stool.
Ways to prevent and ease it
If your doctor expects your cancer or treatment to cause constipation, they may give you tips and prescribe medicine to prevent it. Many of the same steps help if you become constipated.
Everyday tips:
- Drink plenty of liquids. About 8 cups of water or clear liquids a day helps. Coffee and prune juice can have a laxative effect, and hot drinks can help stool move.
- Try to be active every day. Walking, riding a bike, or gentle yoga may be options. You can also do light exercise in a bed or chair. Ask your team what is right for you.
- Eat at the same time each day. A regular routine can help return you to your usual number of bowel movements.
- Keep a record of your bowel movements. Sharing this with your team helps them treat the problem.
- Ask about fiber before adding it. High-fiber foods and fiber supplements can make constipation worse for some people, so check with your doctor first.
Medicines your doctor may recommend
Your doctor may prescribe laxatives to prevent or relieve constipation. Use only medicines and treatments your doctor recommends. Common types include:
- Osmotics, which pull water into the bowel to make stool easier to pass.
- Stool softeners, which soften stool by adding water and fat.
- Stimulant laxatives, which cause the intestines to contract so stool moves along.
Do not use suppositories or enemas unless your doctor recommends them. In some people with cancer, these can cause bleeding, infection, or other harmful effects.
When constipation becomes serious
Long-term constipation can lead to fecal impaction, a serious condition in which hardened stool blocks the colon or rectum. Unlike ordinary constipation, fecal impaction can be life-threatening and needs immediate medical attention.
Signs of fecal impaction include ongoing constipation, a feeling of pressure or incomplete emptying, back or belly pain, changes in urination, nausea and vomiting, and sometimes sudden diarrhea leaking around the blockage. Treating constipation early helps prevent it.
Getting support
Side effects like constipation can be hard to deal with, both physically and emotionally. It's important to ask for support from your health care team. If you are caring for someone with cancer, you can help by encouraging fluids, supporting gentle activity, keeping track of bowel movements, and telling the care team about warning signs.
Watch instead
Animated lessons are in production. Here’s the planned video slate for this topic — each one will be based on the same NCI-sourced explanation you’re reading.
Constipation and Cancer Treatment: the quick overview
A one-breath explanation you can watch before an appointment.
Coming soonConstipation and Cancer Treatment, explained simply
The core ideas with friendly animation and plain language.
Coming soonUnderstanding constipation and cancer treatment — full lesson
A deeper walkthrough covering the key takeaways and common questions.
Coming soonVideo transcript▾
A full, readable transcript will appear here when the video is published — so the lesson is accessible whether you prefer to watch, listen, or read. For now, the article above is the complete text version.
Suggested animation storyboard▾
- 1Open on a calm title card: "Constipation and Cancer Treatment" with the Cancer Explained mark.
- 2Narrator reads the 30-second summary while a soft animated diagram builds on screen: "Constipation is when stool moves slowly through the large intestine, becoming dry and hard. It can be a side effect of cancer treatment, certain medicines, or less activity and diet changes. Drinking fluids, staying active, and medicines your doctor recommends can help. Tell your team early, because untreated constipation can lead to serious problems."
- 3Scene 2: illustrate the idea — "Constipation means stool moves slowly through the large intestine and becomes dry and hard."
- 4Scene 3: illustrate the idea — "It can be caused by some chemotherapy, opioid pain medicines and other drugs, and being less active or eating differently."
- 5Scene 4: illustrate the idea — "Signs include two or fewer bowel movements in a week, hard stool, straining, and belly pain or bloating."
- 6Close on a reminder card: this is educational only; talk with your healthcare team, and a link to the NCI source.
Words to know
Tap any term to see what it means.
Quick knowledge check
According to this article, what is constipation?
Frequently asked questions
▸What counts as constipation during cancer treatment?
Constipation is the slow movement of stool through the large intestine, so it loses fluid and becomes drier and harder. You may have fewer bowel movements than usual, need to push harder, or be unable to go at all. Having two or fewer bowel movements in a week is one sign.
▸Why does cancer treatment cause constipation?
Some types of chemotherapy commonly cause constipation. Many medicines can too, including opioid pain medicines, anti-anxiety drugs, anti-nausea drugs, and diuretics. Being less active and eating different foods during treatment can also lead to constipation.
▸What can I do at home to relieve constipation?
The article suggests drinking plenty of liquids, trying to be active every day, eating at the same time each day, and keeping a record of your bowel movements to share with your team. Ask your doctor before adding fiber, since it can make constipation worse for some people.
▸Can I take a laxative on my own?
Use only medicines and treatments for constipation that your doctor recommends. Do not use suppositories or enemas unless your doctor tells you to, because in some people with cancer these can lead to bleeding, infection, or other harmful side effects.
▸What is fecal impaction and why is it serious?
Fecal impaction is when hardened stool blocks the colon or rectum. Unlike ordinary constipation, it can be life-threatening and needs immediate medical attention. Treating constipation early helps prevent it.
▸When should I call my health care team?
Tell your doctor or nurse if you are constipated so you can get treatment early. Call about severe belly pain, vomiting, fewer than three bowel movements in a week, or other signs of fecal impaction.
Test your understanding
A few quick questions to check what you took away. Not a test of anything medical — just a way to review.
0 of 4 answered
This quiz checks understanding of educational content only. It is not medical advice. Open this quiz on its own page.
Review key terms
Study 10 flashcards built from this topic’s key terms and common questions — flip each card to reveal a plain-language explanation.
Questions to ask your healthcare team
Consider bringing these questions to your next appointment.
- What symptoms or problems should I call you about?
- Should I take medicine for constipation? If so, which one, and which should I avoid?
- How much liquid should I drink each day?
- What foods can help with constipation, and what foods should I avoid?
- Would adding fiber to my diet help me, or could it make things worse?
- Could I meet with a registered dietitian to learn more?
Related learning map
How this explanation connects to 14 other things you can explore — related topics, terms, questions, practice, and its NCI source.
Topic area
Related explanations
Questions this answers