What is thrombocytopenia in cancer treatment?

Thrombocytopenia is a condition in which the number of platelets in the blood is low. Platelets are the cells that help your blood clot and stop bleeding, so when they are low, you may bruise or bleed a lot or very easily and have tiny purple or red spots on your skin.

Some cancer treatments, such as chemotherapy and targeted therapy, can cause thrombocytopenia by lowering the platelet count. If you notice easier bleeding or bruising or the small skin spots, tell your doctor or nurse.

There are steps that may help if you are at increased risk, such as avoiding medicines that contain aspirin or ibuprofen (which can raise bleeding risk), brushing gently with a very soft toothbrush, using an electric shaver instead of a razor, and being careful with sharp objects. Call your doctor for serious problems like bleeding that won't stop or head and vision changes. Your healthcare team can give you a list of medicines to avoid and explain what is safest for you.